There are different types of botulinum toxin products (toxins A and B) with different uses (eye problems, muscle stiffness/spasm, migraine, beauty, overactive bladder). Different brands of this medicine offer different amounts of medicine. Your doctor will choose the right product for you.
Botulinum toxin is used to treat certain eye diseases, such as crossed eyes (strabismus) and uncontrolled blinking (blepharospasm), to treat muscle stiffness/spasm or movement disorders (such as cervical dystonia, torticollis), and Reduce the appearance of wrinkles. It is also used to prevent headaches in patients with very frequent migraines. Botulinum toxin relaxes muscles by preventing the release of a chemical called acetylcholine.
Botulinum toxin is also used to treat overactive bladder in patients who do not respond to other drugs or cannot tolerate the side effects of other drugs. It helps reduce urine leakage, the need to urinate immediately, and frequent visits to the bathroom.
It is also used to treat severe underarm sweating and drooling/excessive saliva. Botulinum toxin works by blocking the chemicals that turn on sweat glands and salivary glands.
After injection, the drug can spread to other parts of the body, causing serious (possibly fatal) side effects. These may occur hours or even weeks after the injection. However, when this drug is used for migraines or skin diseases (such as wrinkles, eye cramps, or excessive sweating), the possibility of such serious side effects is extremely small.
Children who are treated for muscle stiffness/spasms and anyone with certain medical conditions are at the greatest risk of these effects (see the “Precautions” section). Discuss the risks and benefits of this medication with your doctor.
If you experience any of the following very serious side effects, seek medical help immediately: chest pain, difficulty breathing, excessive muscle weakness, irregular heartbeat, severe difficulty swallowing or speaking, loss of bladder control.
Please read the medication guide and the patient information booklet (if available) provided by the pharmacist before starting this medication and every time you inject it. If you have any questions about this information, please consult your doctor or pharmacist.
This medication is administered by injection by an experienced healthcare professional. In the treatment of eye diseases, muscle stiffness/spasm and wrinkles, it is injected into the affected muscle (intramuscular). When used to prevent migraines, it is injected into the muscles of the head and neck. It is injected into the skin (intradermal) to treat excessive sweating. To treat drooling/excessive saliva, this medication is injected into the salivary glands. In the treatment of overactive bladder, it is injected into the bladder.
Your dose, number of injections, injection site, and how often you receive medication will depend on your condition and your response to treatment. For children, the dosage is also based on body weight. Most people will start to see results within a few days to 2 weeks, and the effects usually last for 3 to 6 months.
Because this medicine is given at the site of your condition, most side effects occur near the injection site. Redness, bruising, infection, and pain may occur at the injection site.
When this medicine is used to relax muscles, dizziness, mild difficulty swallowing, respiratory infections (such as cold or flu), pain, nausea, headache, and muscle weakness may occur. There may also be diplopia, drooping or swelling of the eyelids, eye irritation, dry eyes, tearing, decreased blinking, and increased sensitivity to light.
If any of these effects persist or worsen, please notify your doctor or pharmacist immediately. You may need to use protective eye drops/ointments, eye masks, or other treatments.
When this drug is used to prevent migraines, side effects such as headaches, neck pain, and drooping eyelids may occur.
When this drug is used for excessive sweating, side effects such as non-armpit sweating, cold or flu respiratory infections, headache, fever, neck or back pain, and anxiety may occur.
When this drug is used for overactive bladder, side effects such as urinary tract infection, burning/painful urination, fever or dysuria may occur.
Remember, your doctor prescribes this medication because he or she has judged that the benefit to you outweighs the risk of side effects. Many people who use this drug do not have serious side effects.
Very severe allergic reactions to this drug are rare. However, if you notice any symptoms of a severe allergic reaction, seek immediate medical attention, including: itching/swelling (especially face/tongue/throat), skin rash, severe dizziness, difficulty breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, please contact your doctor or pharmacist.
Call your doctor and ask for medical advice about side effects. You can call 1-800-FDA-1088 or visit www.fda.gov/medwatch to report side effects to the FDA.
In Canada-call your doctor for medical advice about side effects. You can report side effects to Health Canada at 1-866-234-2345.
Before using this medication, if you are allergic to it, please tell your doctor or pharmacist; or if you have any other allergies. This product may contain inactive ingredients (such as milk protein found in some products), which may cause allergic reactions or other problems. For more detailed information, please consult your pharmacist.
Before using this medication, please tell your doctor your medical history, especially: bleeding problems, eye surgery, certain eye problems (glaucoma), heart disease, diabetes, signs of infection near the injection site, urinary tract infections, Inability to urinate, muscle/nervous system diseases (such as Lou Gehrig’s disease-ALS, myasthenia gravis), seizures, dysphagia (dysphagia), breathing problems (such as asthma, emphysema, aspiration pneumonia), any botulinum Toxin product treatment (especially the last 4 months).
This medication may cause muscle weakness, drooping eyelids, or blurred vision. Do not drive, use machinery, or perform any activities that require alertness or clear vision until you are sure that you can perform such activities safely. Limit alcoholic beverages.
Certain brands of this medicine contain albumin made from human blood. Although the blood is carefully tested and the medicine goes through a special manufacturing process, the chance of you getting a serious infection due to the medicine is extremely small. For more information, please consult your doctor or pharmacist.
Elderly people who use this drug to treat overactive bladder may be more sensitive to the side effects of this drug, especially its effects on the urinary system.
Children who use this medication to treat muscle cramps may be more sensitive to the side effects of this medication, including difficulty breathing or swallowing. See warning section. Discuss the risks and benefits with your doctor.
This medication should only be used when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not recommended to use cosmetic treatments for wrinkles during pregnancy.
Drug interactions may change the way drugs work or increase the risk of serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/over-the-counter drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change the dosage of any medicine without the approval of your doctor.
Some products that may interact with the drug include: certain antibiotics (including aminoglycoside drugs, such as gentamicin, polymyxin), anticoagulants (such as warfarin), Alzheimer’s disease drugs ( Such as galantamine, rivastigmine, tacrine), myasthenia gravis drugs (such as amphetamine, pyridostigmine), quinidine.
If someone takes an overdose and has severe symptoms such as fainting or difficulty breathing, please call 911. Otherwise, please call the Poison Control Center immediately. U.S. residents can call their local poison control center at 1-800-222-1222. Canadian residents can call the provincial poison control center. Antitoxins are available, but must be used before symptoms of overdose become apparent. Symptoms of overdose may be delayed and may include severe muscle weakness, breathing problems, and paralysis.
It is important to understand the risks and benefits of this therapy. Discuss any questions or concerns with your healthcare professional.
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Conditions of use: The information in this database is intended to supplement rather than replace the professional knowledge and judgment of healthcare professionals. This information is not intended to cover all possible uses, instructions, precautions, drug interactions, or adverse reactions, nor should it be construed to indicate that the use of a particular drug is safe, appropriate, or effective for you or any other person. Before taking any medication, changing any diet, or starting or stopping any course of treatment, you should consult a healthcare professional.
Post time: Aug-30-2021